GOOGLE MAPS is, in my opinion, the best mapping system to use to get directions to Magpie Farms Winery. Start there if you want to find directions from your specific address with Google.
Here are some general directions to get you started:
From the Roscoe and points South East
Take Rt. 17 to Exit 82 41-north approx. 18 miles on the left side.
From the Scranton and points South West
Take I-81 north to I-88 east to Exit 7 north (41 Afton)
Follow 41 north approx. 8 miles from exit. On left side.
From Albany and points North East
I-88 West to Exit 7 directions as above
From Syracuse and points North West
I-81 south to exit 8 to 11 south to 26/206 south/east toward Bainbridge. Stay on 206 for approx. 17 miles Turn Right from 206 onto 41 south exactly 2 miles on your right.